Your trade deadline is when the final game of that specific NFL week ends.
After your trade deadline passes, you can no longer propose or accept trades.
If you have Week 10 selected, this means you can trade up to and including Week 10's games. Once that final game for Week 10 ends, accepting and proposing is no longer allowed.
In most cases, this is generally the end of the Monday Night Football game. Due to COVID-19, it's possible we may see more Tuesday games. In that case, the game trade deadline would be extended to the end of that game on Tuesday.
It is possible for trades to be accepted prior to your trade deadline and then processed afterward. That can happen if you have a review period is enabled:
When can our league trade again?
For dynasty and keeper leagues, trading will reopen as soon as your league's playoff has ended.
We require leagues to be renewed or transitioned each season, and we recommend that you do that first before conducting trades. Otherwise, any moves you make after your league's championship will not carry over to the new version of the league.