Often times, leagues have different rules around how playoff matchups are determined.
Sleeper fantasy football leagues allow commissioners to manually modify playoff seedings so you can do things like giving the highest scorer the second place seed and a bye week.
This feature is available the week leading up to the postseason on the playoff bracket interface for commissioners.
Additionally, the league commissioner will be able to set another bracket for those that did not make playoffs. The commissioner will be able to set it as a consolation bracket (winner's advance) or the toilet bowl) loser's advance).
Finally, the league commissioner will not be able to reseed for the 2nd round like the NFL playoffs.